Related Experiment Video

Updated: Oct 21, 2025

Preparation of Authigenic Pyrite from Methane-bearing Sediments for In Situ Sulfur Isotope Analysis Using SIMS
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Preparation of Authigenic Pyrite from Methane-bearing Sediments for In Situ Sulfur Isotope Analysis Using SIMS

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Sulphur Nuggets

Charussri Leeyaphan1, Panittra Suphatsathienkul1, Pichaya Limphoka1

  • 1Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University.

Medical Mycology Journal
|September 2, 2021
PubMed
Abstract

Insights

Dermoscopy can help diagnose nail fungus (onychomycosis) by identifying specific features. The presence of yellow, clumping, sulphur-nugget-like debris in a ruin appearance is a key indicator for onychomycosis.

Area of Science:

  • Dermatology
  • Mycology
  • Medical Diagnostics

Background:

  • Dermoscopy is an emerging tool for diagnosing and managing nail disorders.
  • The definitive dermoscopic findings for onychomycosis remain under discussion.

Purpose of the Study:

  • To identify dermoscopic features distinguishing onychomycosis (OM) from traumatic onychodystrophy (TOD).

Main Methods:

  • A prospective study involved 65 patients with toenail abnormalities.
  • Patients were classified into OM and TOD groups using mycological tests and clinical assessment.
  • Dermoscopic features were systematically recorded and compared between groups.

Main Results:

  • Onychomycosis was diagnosed in 27 patients (41.5%), all presenting as distal and lateral subungual onychomycosis.
  • Traumatic onychodystrophy was diagnosed in 38 patients.
  • Yellow, clumping, sulphur-nugget-like debris within a ruin appearance was significantly associated with onychomycosis (p=0.002).

Conclusions:

  • The presence of sulphur nuggets in a ruin appearance is a novel and valuable dermoscopic feature for diagnosing onychomycosis.
Keywords:
dermoscopyonychomycosisruin appearancetraumatic onychodystrophy

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