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Infantile Hemangioma Treated with Oral Propranolol: Case Presentation
Nahid Raufi1,2, Arash Nemat3,4
1Department of Dermatology, Maiwand Hospital, Kabul University of Medical Sciences, Kabul, Afghanistan.
Insights
Oral propranolol effectively treats infantile hemangiomas (IHs) in infants. This study shows propranolol medication led to near resolution of a hemangioma in less than six months with no reported side effects.
Area of Science:
- Pediatric Dermatology
- Vascular Biology
Background:
- Infantile hemangiomas (IHs) are common childhood vascular tumors.
- Early intervention is crucial for managing IH growth and potential complications.
Observation:
- A 6-month-old infant presented with a 4-cm gluteal infantile hemangioma.
- Treatment with oral propranolol was initiated after medical evaluation.
Findings:
- Propranolol was administered at escalating doses, starting at 1 mg/kg/day, then maintained at 2 mg/kg/day.
- Significant reduction in hemangioma size and color was observed within one month.
- Complete healing was achieved in under six months, with no reported side effects or relapse.
Implications:
- Oral propranolol is a safe and effective treatment for infantile hemangiomas.
- This approach offers a promising therapeutic option for pediatric vascular lesions.
- Further research can explore optimal dosing and long-term outcomes.
Abstract:
Infantile hemangiomas (IHs) are the most common vascular tumors in childhood. We report the use of propranolol to treat the growth phase of IHs. Propranolol was given to a 6-month-old infant who presented with a 4-cm sharply demarcated hemangioma on his left gluteal region. After relevant evaluation, propranolol was prescribed with a starting dose of 1 mg/kg/day, given in 3 divided doses. Vital signs were monitored during the first 6 hours of treatment. In the absence of side effects, treatment was continued at home with 2 mg/kg/day for six months, and the child was reevaluated after 7 days of treatment and then monthly. After one month, effects on color and growth were noted. Complete healing occurred in less than 6 months. Side effects and relapse were not reported. Propranolol administered orally at 2 mg/kg/day was successful, leading to near resolution of the patient's hemangioma.
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