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The Prevalence of Asthma among Iranian Children and Adolescent: A Systematic Review and Meta-Analysis
Neda Rahimian1, Mohammad Aghajanpour2, Leila Jouybari3
1Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Insights
The prevalence of asthma in Iranian children and adolescents is 6% and 8%, respectively. Wheezing is the most common symptom, while sleep disturbance is the least common, indicating a need for continued prevention strategies.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Asthma is a significant cause of hospitalization in young children.
- Understanding asthma prevalence in Iranian children is crucial for public health planning and family education.
- This study addresses the need for current data on pediatric asthma in Iran.
Purpose of the Study:
- To systematically review and meta-analyze existing studies.
- To estimate the current prevalence of asthma in Iranian children and adolescents.
- To inform public health strategies for asthma prevention and control in Iran.
Main Methods:
- A comprehensive search of international and national databases was conducted until October 2020.
- Included were cross-sectional and original studies, with quality assessed using the NIH tool.
- Pooled prevalence was calculated using a random-effects model, with publication bias assessed by Egger's test.
Main Results:
- 30 studies were analyzed, revealing an overall asthma prevalence of 6% in children and 8% in adolescents.
- Prevalence was slightly higher in boys (9%) compared to girls (8%).
- Wheezing was the most frequent symptom (17-19%), while sleep disturbance was the least common (6%).
Conclusions:
- The prevalence of asthma in Iranian children and adolescents is lower than global averages.
- Current asthma control and prevention strategies in Iran should be maintained and potentially enhanced.
- Future guidelines focusing on asthma control and prevention are recommended for the Iranian health sector.
Background:
Asthma is an important reason for hospitalization in children aged under five years. Information about the current status of asthma in Iranian children can help the Iranian health sector plan carefully and prevent asthma incidence by educating the families. The present systematic review and meta-analysis is aimed at estimating asthma prevalence in Iranian children and adolescents.
Method:
Data were found using keywords such as prevalence, epidemiology, asthma, adolescent, children, pediatrics, Iran in Web of Science, Scopus, PubMed, Cochrane, and Embase databases. Three national databases, including Magiran, Barakat Pharmed Co (Iran medex), and Scientific Information Databank (SID) were searched until 1 October 2020. Cross-sectional and original studies were included in the study, and then, quality assessment was done using the National Institutes of Health's Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. A pooled estimated prevalence of asthma was calculated using Der Simonian-Laird random model. Egger's test was used to evaluate publication bias. The data were analyzed using the STATA software version 16.
Results:
30 studies were selected and investigated. The prevalence of asthma in children and adolescents was 6% and 8%, and the prevalence in boys and girls was 9% and 8%, respectively. Among the asthma symptoms, wheezing had the most prevalence (17% in children and 19% in adolescents) and sleep disturbance had the lowest prevalence (6% in children and 6% in adolescents).
Conclusion:
The prevalence of asthma in Iranian children and adolescents is lower than in the world. Existing strategies should be pursued followed. Also, guidelines for asthma control and prevention should be considered in the future.
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