Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

46.7K
Overview
46.7K
Ethical Dilemmas I01:17

Ethical Dilemmas I

1.3K
Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
1.3K
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

2.6K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.6K
Preparedness and Phobias01:09

Preparedness and Phobias

178
Human fear responses to certain stimuli, such as darkness, heights, deep water, and blood, can often arise despite the absence of direct negative experiences. This phenomenon is rooted in evolutionary psychology, which posits that humans have developed a predisposition to fear stimuli that historically posed significant survival threats. This predisposition, known as preparedness, suggests that early humans who developed a fear of potentially dangerous entities, such as venomous snakes and...
178
Development of Immunocompetence01:22

Development of Immunocompetence

517
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
517
Ethical Issues01:27

Ethical Issues

1.4K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the MAking DEcisions for Kids (MADE for Kids) Survey in a Simulated Setting.

Academic pediatrics·2026
Same author

An exploratory study to determine the feasibility and processes needed to implement the Immunization Neighborhood to increase HPV vaccination among African American adolescents and adolescents in the general population: A multi-partner perspective.

Human vaccines & immunotherapeutics·2026
Same author

Addendum to Nociception and pain in humans lacking a functional TRPV1 channel.

The Journal of clinical investigation·2026
Same author

Communicating about Vaccines in a Politically Contentious Climate.

The New England journal of medicine·2026
Same author

The parent attitudes about childhood vaccines survey at 15: A summary of its use, reach, and scope.

Human vaccines & immunotherapeutics·2026
Same author

Functional coupling between peripheral nociceptor terminals in vivo is enhanced during acute inflammation.

Pain·2025

Related Experiment Video

Updated: Oct 21, 2025

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

1.3K

"It's Like 1998 Again": Why Parents Still Refuse and Delay Vaccines.

Jiana L Ugale1, Heather Spielvogle1, Christine Spina2

  • 1Seattle Children's Research Institute, Seattle, WA, USA.

Global Pediatric Health
|September 2, 2021
PubMed
Summary

US parents frequently refuse or delay childhood vaccines due to concerns about vaccine safety, trust, and perceived low risk of disease. These reasons have remained consistent with previous findings.

Keywords:
health communicationpublic healthvaccination refusalvaccine-preventable diseasesvaccines

More Related Videos

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

10.9K
Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
13:47

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

Published on: May 19, 2020

3.6K

Related Experiment Videos

Last Updated: Oct 21, 2025

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

1.3K
Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

10.9K
Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
13:47

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

Published on: May 19, 2020

3.6K

Area of Science:

  • Pediatrics
  • Public Health
  • Sociology

Background:

  • Parental vaccine refusal and delay pose significant challenges to public health.
  • Understanding current reasons for vaccine hesitancy is crucial for effective interventions.

Purpose of the Study:

  • To update the reasons US parents refuse or delay childhood vaccinations.
  • To identify predominant themes influencing parental vaccine decisions.

Main Methods:

  • Qualitative study conducted from 2018-2019.
  • Involved 33 primary care pediatric providers through focus groups and interviews in Washington and Colorado.
  • Thematic analysis of provider-reported reasons for parental vaccine refusal/delay.

Main Results:

  • Five predominant themes identified: vaccine safety, information sources/decision-makers/timing, low perceived disease risk, lack of trust, and religious objection.
  • Vaccine safety was the most frequently cited reason (45 mentions by 26 providers).
  • Religious objection was the least frequently cited reason (6 mentions by 6 providers).

Conclusions:

  • Provider-reported reasons for parental vaccine refusal or delay in 2018-2019 are similar to those in prior studies.
  • Vaccine safety concerns remain a primary driver of parental hesitancy.
  • Continued research and targeted communication strategies are needed to address parental concerns.