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Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
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Exertional and CrossFit-Induced Rhabdomyolysis.

Michelle Meyer1, Sneha Sundaram, Ingeborg Schafhalter-Zoppoth

  • 1Department of Internal Medicine, California Pacific Medical Center, San Francisco, California.

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|September 2, 2021
PubMed
Summary
This summary is machine-generated.

Exercise-induced rhabdomyolysis, a severe condition, can occur after intense workouts like CrossFit. This case highlights the importance of recognizing and reporting this potentially underdiagnosed condition.

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Area of Science:

  • Sports Medicine
  • Exercise Physiology
  • Clinical Medicine

Background:

  • Exercise-induced rhabdomyolysis is infrequently published outside of case reports.
  • This condition can lead to severe outcomes, including hospitalization and the need for intravenous fluid resuscitation.
  • Understanding the triggers and presentation of rhabdomyolysis is crucial for timely diagnosis and management.

Observation:

  • A 31-year-old female experienced bilateral upper extremity pain and soreness.
  • Symptoms began two days after completing a high-intensity CrossFit workout.
  • Clinical presentation included elevated creatine phosphokinase (CPK), liver function tests, and D-dimer, with normal renal function.

Findings:

  • The patient's creatine phosphokinase (CPK) level was markedly elevated at 18,441 U/L, confirming rhabdomyolysis.
  • Elevated liver enzymes and D-dimer were noted, suggesting systemic effects.
  • Despite severe muscle breakdown, renal function remained preserved.

Implications:

  • CrossFit and similar intense exercise regimens can precipitate rhabdomyolysis.
  • This case underscores the potential for underdiagnosis and underreporting of exercise-induced rhabdomyolysis.
  • Awareness among healthcare providers and fitness professionals is essential for preventing and managing this condition.