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Updated: Oct 21, 2025

The Slice Culture Method for Following Development of Tooth Germs In Explant Culture
Published on: November 13, 2013
Tooth development - Root development
Markus Schaffner1, Herrmann Stich1, Adrian Lussi1
1Klinik für Zahnerhaltung, Präventiv- und Kinderzahnmedizin, Zahnmedizinische Kliniken der Universität Bern.
Abstract:
Tooth development begins in the human embryo 28 to 40 days after ovulation. Epithelial cells grow into the ectomesenchymal parts of the jaw. An epithelial protrusion develops. Further penetration of the epithelial cells into the ectomesenchyma results in the formation of the dental papilla (Figs. 1, 2 and 3). At this point, the cells for the formation of the tooth hard substance are differentiated.
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