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Related Concept Videos

Tooth Anatomy01:21

Tooth Anatomy

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The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
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Teeth01:15

Teeth

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
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Primary and Secondary Growth in Roots and Shoots03:02

Primary and Secondary Growth in Roots and Shoots

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Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
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Folliculogenesis01:20

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Folliculogenesis is the development of ovarian follicles, the specialized structures within the ovarian cortex where oogenesis, or egg development, occurs. This process is essential for female reproductive health and begins during fetal development when primordial follicles are formed. Each primordial follicle comprises a primary oocyte in the center, surrounded by a single layer of squamous pre-granulosa cells. These follicles remain dormant in late prophase I of meiosis until triggered by...
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Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

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Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
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Neurulation01:30

Neurulation

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
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Related Experiment Video

Updated: Oct 21, 2025

The Slice Culture Method for Following Development of Tooth Germs In Explant Culture
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The Slice Culture Method for Following Development of Tooth Germs In Explant Culture

Published on: November 13, 2013

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Tooth development - Root development

Markus Schaffner1, Herrmann Stich1, Adrian Lussi1

  • 1Klinik für Zahnerhaltung, Präventiv- und Kinderzahnmedizin, Zahnmedizinische Kliniken der Universität Bern.

Swiss Dental Journal
|September 2, 2021
PubMed
Summary
This summary is machine-generated.

Human tooth development starts early in embryonic development. Epithelial cells invade the jaw

Keywords:
AmeloblastenHertwig’sche EpithelscheideOdontoblastenZahnpapille

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Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
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Area of Science:

  • Developmental biology
  • Embryology
  • Oral biology

Background:

  • Tooth development is a complex process crucial for oral function.
  • Understanding early embryonic events is key to comprehending tooth formation.

Purpose of the Study:

  • To describe the initial stages of human tooth development.
  • To identify the cellular origins of tooth hard tissues.

Main Methods:

  • Histological examination of human embryonic tissues.
  • Observation of cellular differentiation and tissue morphogenesis.

Main Results:

  • Tooth development initiates 28-40 days post-ovulation.
  • Epithelial cells ingress into the ectomesenchyme, forming the dental papilla.
  • Cells within the dental papilla differentiate for hard tissue formation.

Conclusions:

  • The dental papilla formation is a critical early event in tooth development.
  • This stage establishes the cellular precursors for dentin and enamel formation.