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Related Concept Videos

Regulation of Stroke Volume01:27

Regulation of Stroke Volume

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The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
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Related Experiment Video

Updated: Oct 21, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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COVID-19 Associated Stroke-A Single Centre Experience.

Uma Sundar1, Niteen D Karnik2, Amita Mukhopadhyay3

  • 1Professor, Medicine, Lokmanya Tilak Municipal Medical College and General Hospital (LTMMC&GH), Mumbai, Maharashtra; Corresponding Author.

The Journal of the Association of Physicians of India
|September 2, 2021
PubMed
Summary
This summary is machine-generated.

COVID-19 associated stroke occurred in 1.6% of admissions, with most cases being carotid territory infarcts. In-hospital mortality was high at 55.17%, predicted by low Glasgow Coma Scale scores.

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Vascular Medicine

Background:

  • Neurological complications, including stroke, are recognized sequelae of COVID-19.
  • This study investigates the characteristics and outcomes of stroke patients with COVID-19.

Purpose of the Study:

  • To determine the incidence and clinical features of stroke in COVID-19 patients.
  • To identify predictors of in-hospital mortality in this cohort.

Main Methods:

  • Retrospective analysis of patients admitted with acute stroke and confirmed COVID-19 via RT-PCR.
  • Evaluation of stroke types, affected vascular territories, and in-hospital mortality.
  • Logistic regression analysis to identify mortality predictors.

Main Results:

  • A 1.6% incidence of stroke was observed among 3923 COVID-19 admissions.
  • The majority of strokes were arterial infarcts (73.5%) in the carotid territory.
  • In-hospital mortality was 55.17%, with low Glasgow Coma Scale (GCS) and need for respiratory support predicting mortality.

Conclusions:

  • COVID-19 is associated with a significant incidence of stroke, predominantly carotid artery infarcts.
  • High in-hospital mortality underscores the severity of COVID-19 related neurological events.
  • Low GCS at admission is a critical predictor of mortality in COVID-19 stroke patients.