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Updated: Oct 21, 2025

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The Intermolecular NOE Depends on Isotope Selection: Short Range vs Long Range Behavior

Philipp Honegger1,2, Maria Enrica Di Pietro3, Franca Castiglione3

  • 1Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, United States.

The Journal of Physical Chemistry Letters
|September 2, 2021
PubMed
Summary

By selecting isotopes with different gyromagnetic ratios, researchers can achieve short-ranged intermolecular nuclear Overhauser effect (NOE) signals. This breakthrough enhances molecular structure elucidation for intermolecular interactions.

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