Related Experiment Video

Updated: Oct 21, 2025

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
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Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

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A Giant Left Circumflex Coronary Artery Aneurysm

Grigorios Tsigkas1, Georgios Vasilagkos, Petros Zampakis

  • 1University Hospital of Patras Rion, Patras, 26504, Greece. gregtsig@upatras.gr.

The Journal of Invasive Cardiology
|September 2, 2021
PubMed

Insights

A patient developed a giant coronary artery aneurysm, the largest reported at 63 mm. This occurred 11 years after initial cardiac surgery, highlighting a rare long-term complication.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Interventional Cardiology

Background:

  • A patient presented with severe aortic valve calcification, initially deemed inoperable for aortic valve replacement and aneurysm resection.
  • The patient underwent transcatheter aortic valve implantation (TAVI) due to high surgical risk.

Purpose of the Study:

  • To report a rare case of a giant coronary artery aneurysm developing 11 years post-TAVI.
  • To document the largest giant coronary artery aneurysm identified in medical literature.

Main Methods:

  • Coronary angiography was performed 11 years after the initial TAVI procedure.
  • Imaging revealed a large aneurysm in the coronary artery with intraluminal thrombus.

Main Results:

  • A giant coronary artery aneurysm measuring 63 mm in diameter was identified.
  • The aneurysm contained significant intraluminal thrombus.
  • This represents the largest giant coronary artery aneurysm documented to date.

Conclusions:

  • Giant coronary artery aneurysms can develop as a late complication following cardiac interventions.
  • This case underscores the importance of long-term surveillance for rare vascular complications.

Keywords:
anginacomputed tomography coronary angiographycoronary artery aneurysmgiant coronary aneurysmpericardial tamponaderupturethrombosis

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