Testing the Anti-inflammatory Effects of Curcuminoids in Patients with Colorectal Cancer

Area of Science:

• Oncology
• Natural Products Chemistry
• Immunology

Background:

• Colorectal cancer is a leading cause of cancer mortality globally.
• Curcuminoids from turmeric exhibit antioxidant and anti-inflammatory properties, suggesting potential anti-cancer effects.
• Cytokine profiles are crucial biomarkers in cancer progression and treatment response.

Purpose of the Study:

• To present a protocol for evaluating the impact of curcuminoids on serum cytokine profiles.
• To investigate the role of curcuminoids in managing inflammation and oxidative stress during colorectal cancer chemotherapy.
• To establish a framework applicable to other cancer types.

Main Methods:

• A double-blind, placebo-controlled trial design.
• Inclusion of patients with stage 3 colorectal cancer undergoing chemotherapy.
• Assessment of serum cytokine profiles as a primary outcome measure.

Main Results:

• N/A - This is a protocol description.

Conclusions:

• N/A - This is a protocol description.