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Related Experiment Video

Updated: Jun 16, 2026

Mechanical Ventilation Boot Camp Curriculum

Mechanical Ventilation Boot Camp Curriculum

Published on: March 12, 2018

Computer-based virtual laboratory simulations: LabHEART cardiac physiology practical.

Olivia Monteiro¹, Anand Bhaskar¹, Anna K M Ng¹

¹Department of Biomedical Sciences, Faculty of Medicine, Macau University of Science and Technology, Taipa, Macau S.A.R., China.

Advances in Physiology Education

|September 2, 2021

Summary

This summary is machine-generated.

This study introduces LabHEART software for medical students to explore cardiac excitation-contraction coupling. It offers a virtual, hands-on approach to understanding cardiomyocyte function and drug effects, aligning with ethical animal research principles.

Keywords:

cardiac action potential electrophysiology excitation-contraction coupling ion channels physiology

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Last Updated: Jun 16, 2026

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Published on: March 12, 2018

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

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Published on: February 13, 2021

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Published on: May 27, 2022

Area of Science:

Cardiovascular Physiology
Medical Education Technology

Background:

Traditional cardiomyocyte function demonstrations are resource-intensive and ethically challenging.
Existing methods limit student participation and animal welfare.

Purpose of the Study:

To implement and evaluate the LabHEART software for medical students.
To provide a virtual, hands-on learning tool for cardiac excitation-contraction coupling.
To enhance understanding of physiological and pharmacological aspects of the heart.

Main Methods:

Utilized the LabHEART software for problem-based learning activities.
Students simulated action potentials, calcium changes, and cardiomyocyte contractions.
Applied pharmacological agents and modified biophysical parameters to explore cardiac function and channelopathies.

Main Results:

Students gained hands-on experience with cardiac excitation-contraction coupling.
The software facilitated exploration of drug effects and channelopathies like long QT syndromes.
The activity was adaptable to flipped classroom and online learning formats.

Conclusions:

LabHEART software provides an effective, ethical, and accessible tool for teaching cardiomyocyte function.
The virtual approach enhances student learning and engagement with complex cardiac physiology.
The platform supports flexible implementation and peer-driven learning in medical education.