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Left anterior descending myocardial bridge: Angiographic prevalence and its association to atherosclerosis

Anthony Matta1, Ronan Canitrot2, Vanessa Nader3

  • 1Department of Cardiology, Institute CARDIOMET, University Hospital of Toulouse, Toulouse, France; Faculty of Medicine, Holy Spirit University of Kaslik, Kaslik, Lebanon.

Indian Heart Journal
|September 3, 2021
PubMed

Insights

Left anterior descending myocardial bridges (LADMB) are an inborn variation. This study found LADMB is associated with a reduced risk of atherosclerosis, despite potential complications.

Area of Science:

  • Cardiology
  • Anatomy
  • Vascular Biology

Background:

  • Left anterior descending myocardial bridges (LADMB) are often considered benign.
  • However, LADMB can be an overlooked cause of significant cardiac events.

Purpose of the Study:

  • To determine the prevalence of LADMB.
  • To investigate the association between LADMB and atherosclerosis.

Main Methods:

  • Observational retrospective study.
  • Analysis of coronary angiography data from 35,813 patients (June 2012 - June 2020).
  • Patients divided into LADMB and Non-LADMB groups.

Main Results:

  • LADMB prevalence was 1.42% (510/35,813 patients).
  • Atherosclerosis was significantly less prevalent in the LADMB group (p < 0.001).
  • Higher rates of myocardial infarction with non-obstructive coronary arteries (MINOCA) were seen in acute coronary syndrome LADMB patients.

Conclusions:

  • LADMB is an anatomical variation linked to reduced atherosclerotic risk in the LAD.
  • Awareness of LADMB's potential complications is crucial for high-risk cardiovascular patients.
Abstract

Keywords:
AtherosclerosisLeft anterior descending coronary arteryMINOCAMyocardial bridge

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