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Updated: Oct 21, 2025
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Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model
Published on: February 14, 2021
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No Microscope Needed: A Macroscopic Presentation of Collagenous Colitis.
Amanda L Boyd1, David A Leiman1,2, Darin L Dufault1
1Division of Gastroenterology, Duke University School of Medicine, Durham, NC.
ACG Case Reports Journal
|September 3, 2021
Summary
Microscopic colitis, a cause of chronic diarrhea, often has normal-appearing endoscopic views. However, specific visual signs during endoscopy can suggest this condition, aiding diagnosis and treatment.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Microscopic colitis (MC) presents as chronic secretory diarrhea.
- Diagnosis traditionally relies on histopathology due to normal-appearing mucosa during endoscopy.
Observation:
- Accumulating evidence indicates distinct endoscopic features associated with MC.
- This case highlights macroscopic findings relevant to MC diagnosis.
Findings:
- MC diagnosis requires histopathologic confirmation.
- Endoscopic findings can be indicative of MC, complementing biopsies.
Implications:
- Recognizing endoscopic signs of MC is crucial for timely diagnosis.
- Identifying these features can guide patient management and treatment strategies.
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