A radially interleaved sodium and proton coil array for brain MRI at 7 T

The objective of the current study was to design and build a dual-tuned coil array for simultaneous ²³ Na/¹ H MRI of the human brain at 7 T. Quality factor, experimental B₁⁺ measurements, and electromagnetic simulations in prototypes showed that setups consisting of geometrically interleaved ¹ H and ²³ Na loops performed better than or similar to ¹ H or ²³ Na loops in isolation. Based on these preliminary findings, we built a transmit/receive eight-channel ²³ Na loop array that was geometrically interleaved with a transmit/receive eight-channel ¹ H loop array. We assessed the performance of the manufactured array with mononuclear signal-to-noise ratio (SNR) and B₁⁺ measurements, along with multinuclear magnetic resonance fingerprinting maps and images. The ²³ Na array within the developed dual-tuned device provided more than 50% gain in peripheral SNR and similar B₁⁺ uniformity and coverage as a reference birdcage coil of similar size. The ¹ H array provided good B₁⁺ uniformity in the brain, excluding the cerebellum and brain stem. The integrated ²³ Na and ¹ H arrays were used to demonstrate truly simultaneous quantitative ¹ H mapping and ²³ Na imaging.