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Detection of Residual Host Cell Proteins in Biotherapeutic Drugs by Concatenated 2D LC-MS/MS

Feng Yang1, Delia Li2, Donald E Walker2

  • 1Protein Analytical Chemistry, Genentech, South San Francisco, CA, USA. yang.feng@gene.com.

Methods in Molecular Biology (Clifton, N.J.)
|September 3, 2021
PubMed

Keywords:
Data-dependent acquisitionFraction concatenationHost cell proteinMonoclonal antibodyTandem Mass spectrometryTwo-dimensional liquid chromatography

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