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Related Experiment Video

Updated: Oct 21, 2025

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

Multiscale communication in cortico-cortical networks.

Vincent Bazinet¹, Reinder Vos de Wael¹, Patric Hagmann²

¹McConnell Brain Imaging Centre, Montréal Neurological Institute, McGill University, Montréal, Canada.

|September 3, 2021

Summary

Brain regions exhibit diverse communication preferences, with unimodal areas favoring local signaling and multimodal areas favoring global signaling across the brain network. This reveals scale-specific structure-function coupling shaping brain organization.

Keywords:

Brain networks Connectome Hierarchy Network communication Structure-function

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Last Updated: Oct 21, 2025

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Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

Area of Science:

Neuroscience
Network Science
Computational Biology

Background:

Brain networks operate across local and global topological scales.
Information exchange occurs via direct neighbors (local) or distant regions (global).

Purpose of the Study:

To investigate how cortico-cortical network organization mediates localized and global communication.
To understand how signal transmission range on the white matter connectome influences brain communication patterns.

Main Methods:

Parametrically tuning signal transmission range on the white matter connectome.
Analyzing communication preferences across multiple topological scales.
Examining region- and scale-specific structure-function coupling.

Main Results:

Brain regions demonstrate varying preferred communication scales.
Unimodal regions prefer local communication; multimodal regions prefer global communication.
Functional connectivity in unimodal regions arises from local, monosynaptic circuits; transmodal regions rely on global, polysynaptic circuits.

Conclusions:

Communication preferences are heterogeneous across the cortex.
These preferences shape regional differences in structure-function coupling.
Brain organization is influenced by the interplay of local and global communication strategies.