Analytical and regulatory considerations to mitigate highly hazardous toxins from environmental matrices

The ubiquitous occurrence, toxicological influence, and bioaccumulation of toxic entities, e.g., pesticides and toxic elements in the environment, biota, and humans, directly or indirectly, are posing severe social, ecological, and human health concerns. Much attention has been given to the rising bioaccumulation of toxins and their adverse impact on various environmental matrices. For example, the inappropriate and exacerbated use of xenobiotics and related hazardous substances have caused the deterioration of the agricultural environment, e.g., fertile soils where plants are grown. Moreover, the harmful toxins have negatively impacted human health through the trophic chains. However, the analytical and regulatory considerations to effectively monitor and mitigate any or many pesticides and toxic elements from environmental matrices are still lacking in the existing literature. For decades, the scientific community has overseen the consequences caused by pollutants, however, the improvement of analytical detection methods and regulatory considerations are not yet fully covered. This review covers the notable literature gap by stressing the development and deployment of robust analytical and regulatory considerations for an efficient abatement of hazardous substances. Following detailed information on occurrence, toxicological influence, and bioaccumulation of pesticides and toxic elements, the most relevant analytical detection tools and regulatory measures are given herein, with suitable examples, to mitigate or reduce the damage caused by these pollutants.