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Updated: Oct 21, 2025

Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
Published on: April 18, 2011
Muscular activity comparison between non-amputees and transfemoral amputees during normal transient-state walking
Pouyan Mehryar1, Mohammad S Shourijeh2, Tahmineh Rezaeian3
1Institute of Design, Robotic, and Optimisation, Mechanical Engineering, University of Leeds, Leeds, UK; Healthcare Innovation Centre, School of Health & Life Sciences, Teesside University, Middlesborough, UK.
Research Question:
Would there be differences in muscle activation between healthy subjects' (HS) dominant leg and transfemoral amputees' (TFA) intact-leg/contralateral-limb (IL) during normal transient-state walking speed?
Methods:
The muscle activation patterns are obtained by calculating the linear envelope of the EMG signals for each group. The activation patterns/temporal changes are compared between-population using statistical parametric mapping (SPM).
Results:
Individual muscle activity showed significant differences in all muscles except vastus lateralis (VL), semitendinosus (SEM) and tensor fascia latae (TFL) activities.
Significance:
The information could be used by the therapists to prevent secondary physical conditions and prosthetic companies to improve the mobility of the amputees.

