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Updated: Oct 21, 2025

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
[Clinical and bacteriological profile in patients with knee tumor arthroplasty and early periprosthetic infection]
A Alcántara-Corona1, G Cario-Méndez1, R A Amaya-Zepeda1
1Servicio de Cirugía de Tumores Óseos, Unidad Médica de Alta Especialidad (UMAE) Hospital de Ortopedia. «Dr. Victorio de la Fuente Narváez», Instituto Mexicano del Seguro Social (IMSS). Ciudad de México. México.
Introduction:
At the national and international levels, there are few studies on early knee tumor periprosthetic infection. We present a review of patients operated by knee tumor arthroplasty, obtaining information on the clinical and bacteriological profile of early tumor periprosthetic infections.
Material And Methods:
Observational, retrospective and descriptive study, review of patient records with knee tumor replacement, from 1 January 2013, to 31 December 2017 and minimum follow-up of 2 years.
Results:
35 patients with average age 32. Left knee 71.4%, 77.1% distal femur, 54.2% was osteosarcoma. Complications in 82.8% of patients, prosthetic retention 62.8%; periprosthetic infection accounts for 34.2% of early complications in 90% of cases. Osteosarcomas and GCT had early infection in equal proportion (44%). The most common comorbidity was overweight/obesity at 66%, smoking by 55%. 55% of infected patients received chemotherapy. 58% of the isolated bacteria were Staphylococcus sp. 83.3% of bacteria showed antibiotic resistance. 66% of infected patients required radical management.
Conclusions:
Early periprosthetic infection represents a devastating pathology in our institution. Prosthetic retention is achieved at 66%. In our unit the bacteriological profile is resistant.

