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Characteristics of hospitalised COVID-19 patients and parameters associated with severe pneumonia

Onur Turan1, Arzu Mirici2, Serap Duru Akçalı3

  • 1Chest Diseases Department, Izmir Katip Celebi University Atatürk Research and Training Hospital, İzmir, Turkey.

International Journal of Clinical Practice
|September 4, 2021
PubMed

Insights

This study analyzed hospitalized COVID-19 patients in Turkey, finding that advanced age, low blood pressure, anemia, and elevated CRP and LDH levels predict severe pneumonia. These factors are crucial for assessing COVID-19 severity.

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Public Health

Background:

  • The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has had a significant global impact, including in Turkey.
  • Understanding the characteristics of hospitalized patients is crucial for managing the disease and predicting outcomes.

Purpose of the Study:

  • To analyze the demographic, clinical, laboratory, and radiological characteristics of hospitalized COVID-19 patients in Turkey.
  • To identify parameters associated with severe pneumonia in COVID-19 patients.

Main Methods:

  • Retrospective analysis of hospitalized COVID-19 patients with positive naso-oropharyngeal swabs.
  • Data collected included demographics, symptoms, laboratory findings (CRP, LDH, lymphopenia), and radiological features.
  • Multivariate logistic regression was used to identify risk factors for severe pneumonia.

Main Results:

  • The study included 1013 patients, with a mean age of 53.7 years; 57.6% were male.
  • Common symptoms included cough, fatigue, and fever. Hypertension and diabetes were prevalent comorbidities.
  • 84.9% of patients had pneumonia, and 28.1% had severe pneumonia. Independent risk factors for severe pneumonia included advanced age, hypotension, anemia, and elevated CRP and LDH levels.

Conclusions:

  • This multicenter study provides insights into COVID-19 characteristics and pneumonia severity in Turkey.
  • Key indicators for severe COVID-19 pneumonia include age, blood pressure, complete blood count, and biochemical tests like CRP and LDH.
Abstract

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