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Outcomes into adulthood of infants born extremely preterm

Jeanie L Y Cheong1, Anjali Haikerwal2, Peter J Anderson3

  • 1Neonatal Services, Royal Women's Hospital, Melbourne, Australia; Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia; Department of Obstetrics & Gynaecology, University of Melbourne, Melbourne, Australia.

Seminars in Perinatology
|September 6, 2021
PubMed

Insights

Infants born extremely preterm face ongoing developmental and health challenges into adulthood. However, their self-reported quality of life remains good, highlighting the need for tailored interventions.

Area of Science:

  • Neonatal Medicine
  • Developmental Pediatrics
  • Adult Health

Background:

  • Increasing survival rates of extremely preterm infants mean more individuals reach adulthood.
  • Established developmental delays and disabilities persist from childhood into later life.
  • Emerging physical and mental health issues become apparent with age in this population.

Purpose of the Study:

  • To examine the long-term health trajectory of extremely preterm survivors.
  • To assess the quality of life in adulthood for individuals born extremely preterm.
  • To identify future research and intervention needs for this growing population.

Main Methods:

  • Longitudinal follow-up of extremely preterm survivors into adulthood.
  • Assessment of developmental, physical, and mental health outcomes.
  • Evaluation of self-reported quality of life measures.

Main Results:

  • Extremely preterm survivors experience persistent developmental challenges.
  • Adult health issues, including physical and mental health concerns, are increasingly evident.
  • Despite health challenges, self-reported quality of life is generally positive.

Conclusions:

  • Extremely preterm individuals require ongoing support beyond childhood.
  • Age-appropriate interventions are crucial to optimize health and development in adulthood.
  • Further research should focus on tailored support strategies for long-term well-being.

Keywords:
Blood pressureCognitive outcomesExtremely low birth weightExtremely pretermMental healthRespiratory health

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