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Updated: Aug 11, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Non coronary applications of cardiac computed tomography: A review
Muhammad Usman Aziz1, Padma Manapragada1, Satinder P Singh1
1The University of Alabama at Birmingham, Department of Diagnostic Radiology, Birmingham, AL, United States.
Insights
Cardiac computed tomography (CCT) offers advanced, noninvasive imaging for various heart conditions. This review highlights CCT
Area of Science:
- Cardiology
- Medical Imaging
- Radiology
Background:
- Cardiovascular disease is a leading cause of death globally.
- Acquired heart conditions, including valvular issues and coronary artery disease, contribute significantly to mortality.
- Cardiac computed tomography (CCT) has advanced, improving image quality for cardiac assessments.
Purpose of the Study:
- To review the non-coronary applications of cardiac CT.
- To explore CCT's role in valvular assessment, pulmonary vein isolation, and left atrial appendage evaluation.
Main Methods:
- Review of current literature and technological advancements in cardiac CT.
- Focus on non-coronary indications and their diagnostic utility.
- Emphasis on image quality, radiation dose, and acquisition speed.
Main Results:
- CCT provides high temporal and spatial resolution for cardiac imaging.
- It offers noninvasive assessment of cardiac structure, function, and valvular pathologies.
- CCT aids in evaluating valvular vegetation, masses, and intracardiac thrombus.
Conclusions:
- CCT is a valuable, noninvasive tool for diagnosing and managing non-coronary cardiac conditions.
- Its applications extend to pre- and post-intervention management in valvular diseases and electrophysiology.
- CCT facilitates procedures like pulmonary vein isolation and transcatheter left atrial appendage occlusion.
Abstract:
Acquired heart diseases including valvular pathologies and conduction abnormalities, along with coronary artery disease make cardiovascular disease one of the major causes of mortality and morbidity worldwide. Advances in cardiac computed tomography (CCT) have led to markedly improved image quality for assessment of several coronary and noncoronary cardiac abnormalities. With the latest versions of CT scanners, image acquisition can be completed within a few seconds, in a single breath hold and with much less radiation exposure, thus making CT an even more attractive diagnostic tool with its high temporal and excellent spatial resolution. Additional advantages are its noninvasive nature, wide availability, fast image acquisition and ability to provide additional data about the cardiac structure, function, valvular motion, and presence or absence of valvular vegetation, mass or intracardiac thrombus. These factors can result in change in management in many valvular pathologies pre- and post-intervention, and in electrophysiological procedures. The goal of this article is to review applications of cardiac CT in non-coronary indications including valvular assessment, pulmonary vein isolation procedure, and left atrial appendage evaluation for its transcatheter occlusion.
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