Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Urinary Tract Infection IV: Nursing Management

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...

The Micturition Reflex

The Micturition Reflex

Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...

Urinary Tract Calculi III: Medical Management

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...

Urinary Bladder

Urinary Bladder

The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...

Urinary Tract Calculi V: Nursing Management

Urinary Tract Calculi V: Nursing Management

AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...

Irritable Bowel Syndrome III: Medical and Nursing Management

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Urodynamics assessment in patients with multiple sclerosis.

BJUI compass·2026

Same author

Comparing the clinical and cost-effectiveness of various washout policies in preventing catheter associated complications in adults living with long-term catheters: synopsis of the CATHETER II RCT.

Health technology assessment (Winchester, England)·2026

Same author

How Could the Proposed International Continence Society (ICS) Global Urodynamics Data Repository (GUDRep) Demonstrate the Clinical Role and Cost Effectiveness of Urodynamics in Individual Patients? ICI-RS 2025.

Neurourology and urodynamics·2025

Same author

Which Patients With Dysfunctional Voiding Respond Well to Sacral Neuromodulation? ICI-RS 2025.

Neurourology and urodynamics·2025

Same author

Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms: FUTURE, a superiority RCT and economic evaluation.

Health technology assessment (Winchester, England)·2025

Same author

A Medium to Long-Term Study Comparing Stress Urinary Incontinence Procedures.

Neurourology and urodynamics·2025

Search research articles

Related Experiment Video

Updated: Oct 21, 2025

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Update on the management of overactive bladder.

Christina Fontaine¹, Emma Papworth², John Pascoe³

¹Specialist Registrar in Urology, University Hospitals Plymouth, Derriford Road, Devon, PL6 8AU, UK.

Therapeutic Advances in Urology

|September 6, 2021

Summary

This summary is machine-generated.

Overactive bladder (OAB) syndrome management includes behavioral therapy and medications. Refractory cases benefit from treatments like botulinum A and sacral neuromodulation, yet patient dissatisfaction persists, highlighting the need for new therapies.

Keywords:

BOTOX antimuscarinic beta-agonist overactive bladder sacral neuromodulation urinary incontinence

More Related Videos

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

Real-Time Void Spot Assay

Real-Time Void Spot Assay

Published on: February 10, 2023

Related Experiment Videos

Last Updated: Oct 21, 2025

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

Real-Time Void Spot Assay

Real-Time Void Spot Assay

Published on: February 10, 2023

Area of Science:

Urology
Nephrology

Background:

Overactive bladder (OAB) syndrome is a prevalent condition characterized by urinary urgency, frequency, and nocturia.
Diagnosis relies on patient-reported symptoms, with numerous treatment options available.

Purpose of the Study:

To review current management strategies for overactive bladder (OAB).
To highlight the efficacy of established treatments for refractory OAB.
To underscore the ongoing need for novel therapeutic approaches due to treatment dissatisfaction.

Main Methods:

Review of clinical guidelines and established treatments for OAB.
Discussion of multidisciplinary approaches including behavioral therapy and pharmacotherapy.
Evaluation of advanced treatments such as intradetrusor botulinum A, sacral neuromodulation, percutaneous tibial nerve stimulation, and augmentation cystoplasty.

Main Results:

Behavioral therapy and pharmacotherapy are first-line treatments, initiated in primary care.
Intradetrusor botulinum A and sacral neuromodulation are safe and effective for refractory OAB.
Percutaneous tibial nerve stimulation and augmentation cystoplasty are efficacious in specific patient groups.

Conclusions:

Despite available treatments, a significant rate of patient dissatisfaction and discontinuation exists.
There is a persistent need for the development of emerging therapies to improve OAB management outcomes.