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Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

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Tuberculous severe acute colitis. A case report.

A Haddad^1,2, A Sebai^1,2, B Chelly^3,2

¹Surgery Department A, La Rabta Hospital, Tunis, Tunisia.

Annals of Medicine and Surgery (2012)

|September 6, 2021

Summary

This summary is machine-generated.

Tuberculous severe acute colitis is a rare, life-threatening condition. Early diagnosis and treatment are crucial for survival, especially in immunocompromised individuals.

Keywords:

Mycobacterium tuberculosis Severe acute colitis Tuberculosis

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Area of Science:

Gastroenterology
Infectious Diseases
Pathology

Background:

Intestinal tuberculosis accounts for 2% of global tuberculosis cases.
Tuberculous severe acute colitis is a rare and life-threatening condition, with only five previously reported cases.
This condition typically affects immunocompromised patients.

Observation:

A patient presented with severe, idiopathic acute colitis, progressing to septic shock and colic perforation despite broad-spectrum antibiotics and corticosteroids.
Colectomy was performed, and subsequent microbiology and pathology confirmed tuberculous colitis.
Extended colonic inflammation was identified as a significant predictor of mortality.

Findings:

Diagnosis of tuberculous severe acute colitis is challenging due to non-specific symptoms.
Microbiology and pathology are essential for confirming the diagnosis of colonic tuberculosis.
Abdominal CT scans may suggest the diagnosis of tuberculous severe acute colitis.

Implications:

Prompt diagnosis and initiation of antituberculous treatment are critical for patient survival.
Understanding risk factors like extended colonic inflammation can guide clinical management.
This case highlights the importance of considering tuberculosis in severe acute colitis, particularly in at-risk populations.