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Related Concept Videos

Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

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Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
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Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

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The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
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Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

399
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
399
Urinary Tract Calculi I: Introduction01:28

Urinary Tract Calculi I: Introduction

160
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
160
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

156
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
156
Urologic Endoscopic Procedure: Cystoscopic Examination01:28

Urologic Endoscopic Procedure: Cystoscopic Examination

685
Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...
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Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology
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Ceftriaxone-associated pseudolithiasis.

Masaru Kurihara1, Yasuharu Tokuda1

  • 1Department of Hospital Medicine Urasoe General Hospital Okinawa Japan.

Journal of General and Family Medicine
|September 6, 2021
PubMed
Summary

Ceftriaxone can cause pseudolithiasis, a condition mimicking gallstones. This study highlights the importance of recognizing this drug-induced phenomenon to avoid unnecessary interventions.

Area of Science:

  • Pharmacology
  • Gastroenterology
  • Radiology

Background:

  • Ceftriaxone is a widely used third-generation cephalosporin antibiotic.
  • Pseudolithiasis is a rare adverse effect associated with certain medications.
  • Distinguishing pseudolithiasis from true cholelithiasis is clinically significant.

Purpose of the Study:

  • To investigate the occurrence and characteristics of ceftriaxone-associated pseudolithiasis.
  • To raise awareness among clinicians regarding this potential adverse drug reaction.

Main Methods:

  • Review of relevant medical literature and case reports.
  • Analysis of diagnostic imaging findings in patients with suspected pseudolithiasis.
  • Correlation of pseudolithiasis occurrence with ceftriaxone administration.
Keywords:
ceftriaxonepseudolithiasis

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Main Results:

  • Ceftriaxone-associated pseudolithiasis presents as echogenic material in the gallbladder, mimicking gallstones on ultrasound.
  • The phenomenon is typically transient and resolves after discontinuation of ceftriaxone.
  • No significant complications were reported in most cases.

Conclusions:

  • Ceftriaxone can induce a reversible pseudolithiasis.
  • Awareness and appropriate diagnostic workup are crucial to differentiate from true gallstones.
  • This condition highlights the importance of considering drug effects in differential diagnosis.