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Related Experiment Video

Updated: Oct 21, 2025

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Published on: June 4, 2020

Thromboelastography in elective total hip arthroplasty.

Patryck Lloyd-Donald¹, Wen-Shen Lee¹, Guo-Ming Liu¹

¹Department of Anesthesia, Austin Health, Heidelberg 3084, Victoria, Australia.

World Journal of Orthopedics

|September 6, 2021

Summary

This summary is machine-generated.

Patients undergoing total hip arthroplasty (THA) remain hypercoagulable post-surgery despite enoxaparin prophylaxis. Thromboelastography (TEG) monitoring may guide more optimal anticoagulation and hemostatic management for these high-risk patients.

Keywords:

Anesthesia Hip arthroplasty Hypercoagulability Orthopedic Surgery Thrombelastography

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A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

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Area of Science:

Orthopedic Surgery
Hematology
Anesthesiology

Background:

Hypercoagulability is a key risk factor for venous thromboembolism (VTE) after total hip arthroplasty (THA).
Thromboelastography (TEG) is utilized to assess coagulation status in THA patients.

Purpose of the Study:

To evaluate coagulation status using TEG in THA patients receiving standard enoxaparin chemoprophylaxis for VTE.
To compare TEG findings with conventional coagulation tests.

Main Methods:

Retrospective analysis of TEG data from patients undergoing primary elective THA.
TEG samples analyzed pre-incision, intraoperatively, and for 5 days postoperatively.
Conventional coagulation tests performed preoperatively and on postoperative day 5.

Main Results:

TEG revealed a progressive postoperative hypercoagulable state, indicated by elevated maximum amplitude.
Spinal anesthesia (SA) was associated with transient intraoperative hypercoagulability.
Conventional tests showed normal results except for elevated plasma fibrinogen on postoperative day 5.

Conclusions:

THA patients exhibit a persistent hypercoagulable state despite standard VTE prophylaxis.
Enhanced anticoagulation and/or perioperative hemostatic monitoring with TEG may benefit this patient group.
TEG offers a more sensitive measure of hypercoagulability compared to conventional tests in the perioperative THA setting.