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Updated: Oct 21, 2025

Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D
Published on: May 19, 2018
Novel Protein Therapeutics Created Using the Elastin-Like Polypeptide Platform
1Departments of Neurology, Cell and Molecular Biology, and Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Abstract:
Elastin-like polypeptides (ELPs) are bioengineered proteins that have a unique physical property, a thermally triggered inverse phase transition, that can be exploited for drug delivery. ELP-fusion proteins can be used as soluble biologics, thermally targeted drug carriers, self-assembling nanoparticles, and slow-release drug depots. Because of their unique physical characteristics and versatility for delivery of nearly any type of therapeutic, ELP-based drug delivery systems represent a promising platform for biologics development.
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