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Related Concept Videos

Overview of Pulmonary Circulation01:19

Overview of Pulmonary Circulation

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The pulmonary circulation is a vital system in our body that acts as a bridge between the respiratory and cardiovascular systems. It serves as a transport network for deoxygenated blood from the heart to the lungs and then returns oxygen-rich blood back to the heart.
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
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Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
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Overview of Systemic Veins01:11

Overview of Systemic Veins

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Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...
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Pneumothorax-II01:27

Pneumothorax-II

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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
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Overview of Systemic and Pulmonary Circulation01:15

Overview of Systemic and Pulmonary Circulation

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The systemic and pulmonary circuits are crucial components of the circulatory system, working together to transport blood between the heart, lungs, and the rest of the body. The process begins with pulmonary circulation, where deoxygenated blood is pumped from the right ventricle to the lungs via the pulmonary trunk and arteries. Upon reaching the lungs, the blood becomes oxygenated and returns to the heart, specifically to the left atrium, via the pulmonary veins.
The oxygenated blood is sent...
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Fetal Circulation01:14

Fetal Circulation

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Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
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Related Experiment Video

Updated: Oct 21, 2025

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
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Common pulmonary vein atresia.

Thomas Glenn1, Jose Honold2, Beth F Printz1

  • 11Division of Cardiology, Department of Pediatrics, University of California San Diego, Rady Children's Hospital San Diego, San Diego, CA, USA.

Cardiology in the Young
|September 6, 2021
PubMed
Summary
This summary is machine-generated.

Common pulmonary vein atresia is a rare congenital heart defect causing severe cyanosis in newborns. This case highlights the importance of considering this condition in neonates with profound cyanosis unresponsive to standard treatments.

Keywords:
CHDCommon pulmonary venous atresiacyanosistotal anomalous pulmonary venous return

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Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease
  • Neonatal Medicine

Background:

  • Profound cyanosis in neonates often indicates critical congenital heart disease (CHD).
  • Alprostadil infusion is commonly used for suspected duct-dependent lesions in neonates.
  • Diagnostic challenges can arise in identifying complex cardiac anatomies in critically ill infants.

Purpose of the Study:

  • To report a rare case of common pulmonary vein atresia in a neonate.
  • To emphasize the diagnostic considerations for severe cyanosis in newborns.
  • To discuss the rarity and clinical implications of common pulmonary vein atresia.

Main Methods:

  • Case presentation of a neonate with profound cyanosis.
  • Diagnostic imaging including echocardiography and cardiac CT scan.
  • Clinical decision-making regarding surgical intervention and withdrawal of care.

Main Results:

  • Cardiac CT revealed a nearly atretic common pulmonary vein with systemic venous drainage.
  • Echocardiography had difficulty delineating pulmonary venous anatomy.
  • High mortality risk associated with operative repair led to compassionate withdrawal of care.

Conclusions:

  • Common pulmonary vein atresia is an exceedingly rare condition, with fewer than 40 reported cases.
  • This diagnosis should be considered in neonates presenting with severe cyanosis.
  • Early and accurate diagnosis is crucial, although treatment options may be limited due to anatomical complexity.