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Efficacy of acceptance and commitment therapy for people with type 2 diabetes: Systematic review and meta-analysis
Ryo Sakamoto1, Yoichi Ohtake2,3, Yuki Kataoka4,5,6,7
1Department of Psychosomatic Medicine, Faculty of Medicine, Kindai University, Osakasayama, Japan.
Aims/Introduction:
This systematic review and meta-analysis aimed to investigate the efficacy and safety of acceptance and commitment therapy (ACT) for people with type 2 diabetes mellitus.
Materials And Methods:
Several electronic databases were examined on 16 January 2021, including PubMed, CENTRAL, PsycINFO, International Clinical Trials Registry Platform and ClinicalTrials.gov. Randomized controlled trials were included to compare ACT with usual treatment for people with type 2 diabetes reported in any language. Primary outcome measures were glycated hemoglobin, self-care ability assessed by the summary of diabetes self-care activities and all adverse events. The secondary outcome measure was acceptance assessed by the acceptance and action diabetes questionnaire.
Results:
Of 678 publications initially identified, three trials were included in the meta-analysis. ACT resulted in a reduction in glycated hemoglobin (mean difference -0.62 points lower in the intervention group; 95% confidence interval -1.07 to -0.16; I2 = 0%; low-quality evidence). In addition, ACT increased the score of the summary of diabetes self-care activities (mean difference 8.48 points higher in the intervention group; 95% confidence interval 2.16-14.80; high-quality evidence). Adverse events were not measured in all trials. ACT increased scores of the acceptance and action diabetes questionnaire (mean difference 5.98 points higher in the intervention group; 95% confidence interval, 1.42-10.54; I2 = 43%; low-quality evidence).
Conclusions:
ACT might reduce glycated hemoglobin, and increase self-care ability and acceptance among people with type 2 diabetes.
Insights
Acceptance and Commitment Therapy (ACT) may improve type 2 diabetes management by reducing glycated hemoglobin and enhancing self-care abilities. This therapy also increases patient acceptance, supporting better health outcomes in individuals with type 2 diabetes mellitus.
Area of Science:
- Behavioral Psychology
- Endocrinology
- Clinical Psychology
Background:
- Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder requiring comprehensive management strategies.
- Psychological interventions are increasingly recognized for their role in improving T2DM self-management and clinical outcomes.
- Acceptance and Commitment Therapy (ACT) is a mindfulness-based behavioral intervention that promotes psychological flexibility.
Purpose of the Study:
- To systematically review and meta-analyze the efficacy and safety of ACT in individuals diagnosed with type 2 diabetes mellitus.
- To evaluate ACT's impact on key glycemic control markers, self-care behaviors, and psychological acceptance in T2DM patients.
Main Methods:
- A systematic literature search was conducted across major electronic databases (PubMed, CENTRAL, PsycINFO, etc.) up to January 16, 2021.
- Randomized controlled trials comparing ACT with usual care for T2DM were included, irrespective of language.
- Primary outcomes included glycated hemoglobin (HbA1c), diabetes self-care activities, and adverse events; acceptance was a secondary outcome.
Main Results:
- Meta-analysis of three trials revealed that ACT significantly reduced glycated hemoglobin levels (MD -0.62; 95% CI -1.07 to -0.16) with low-quality evidence.
- ACT demonstrated a significant improvement in diabetes self-care activities scores (MD 8.48; 95% CI 2.16-14.80) based on high-quality evidence.
- Acceptance, measured by the Acceptance and Action Diabetes Questionnaire, significantly increased (MD 5.98; 95% CI 1.42-10.54) with low-quality evidence.
Conclusions:
- ACT shows potential as an effective intervention for improving glycemic control in type 2 diabetes.
- The therapy enhances self-care abilities and psychological acceptance, crucial components for managing T2DM.
- Further research with high-quality evidence is warranted to confirm the safety and long-term benefits of ACT in T2DM management.
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