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Anterior chamber depth measurement using Pentacam and Biograph in children
Hassan Hashemi1, Samira Heydarian2, Mehdi Khabazkhoob3
1Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Insights
The Pentacam and Biograph devices show good agreement for measuring anterior chamber depth in children, suggesting they can be used interchangeably for accurate pediatric eye assessments.
Area of Science:
- Ophthalmology
- Biometry
- Pediatric Optometry
Background:
- Accurate anterior chamber depth (ACD) measurement is crucial in pediatric eye care.
- Limited data exists on the agreement between rotating Scheimpflug imaging (Pentacam HR) and optical biometry (Lenstar LS 900) in children.
Purpose of the Study:
- To evaluate the agreement between Pentacam and Biograph for measuring ACD in a pediatric population.
- To determine the interchangeability of these two devices for pediatric ACD assessment.
Main Methods:
- A cross-sectional study involving 4882 eyes of students aged 6-18 years in Shahroud, Iran.
- Anterior chamber depth was measured using both Pentacam HR and Lenstar LS 900.
- Data analysis included Bland-Altman plots to assess agreement and intraclass correlation coefficients.
Main Results:
- The mean ACD measured by Pentacam (3.09 ± 0.26 mm) was slightly higher than by Biograph (3.04 ± 0.24 mm) (p < 0.001).
- The 95% limits of agreement ranged from -0.19 to 0.09 mm.
- Agreement improved with age, and the highest correlation was observed in myopic participants.
Conclusions:
- Pentacam and Biograph demonstrate acceptable agreement for measuring anterior chamber depth in children.
- These devices can be considered interchangeable for ACD measurements in pediatric eye examinations.
Clinical Relevance:
Accurate measurement of the anterior chamber depth is very important. There is no report regarding the agreement between rotating Scheimpflug imaging (Pentacam HR) and biograph (Lenstar LS 900) in children. This study therefore explores the agreement between Pentacam and Biograph in measuring anterior chamber depth in children.
Background:
This study aims to determine the agreement between Pentacam and Biograph in measuring anterior chamber depth in children.
Methods:
The participants were students living in urban and rural areas of Shahroud, Iran, selected through cluster sampling. The students were transported to the examination site to undergo imaging and optometric tests. Pentacam imaging was then conducted, and biograph was used to measure biometric components. In this report, the anterior chamber depth was calculated from the corneal endothelium.
Results:
Of 6624 students selected randomly, 5620 participated in the study. After applying the exclusion criteria, 4882 eyes were included in the final analysis. The mean anterior chamber depth measured by the Pentacam (3.09 ± 0.26 mm) was higher than that of biograph (3.04 ± 0.24 mm) (p < 0.001). The 95% limit of agreement (LOA) between the two devices was -0.19 to 0.09 mm. The variation of the difference between the two devices decreased, LOA became narrower, and the correlation coefficient of the devices increased with ageing. The highest intraclass correlation coefficient was seen among myopic (0.974) participants. The 95% LOA was -0.20 to 0.12 mm in hyperopic, -0.17 to 0.07 mm in myopic and -0.19 to 0.09 mm in emmetropic participants.
Conclusion:
The Pentacam and Biograph can be used interchangeably for measuring the anterior chamber depth in children.

