Related Experiment Video
Updated: Oct 21, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Foreword: Advances in Hemoglobinopathies
1Quisisana Hospital, Ferrara. vdesanctis@libero.it.
Insights
Advances in Hemoglobinopathies highlight endocrine complications and treatment effects in patients with beta-thalassemia and sickle cell disease. Research covers insulin response, immigration screening, and impacts on growth and puberty.
Area of Science:
- Hematology
- Endocrinology
- Public Health
Background:
- Acta Biomedica Parmensis launches an annual update on
Discussion:
- This update addresses critical aspects of hemoglobinopathies, including endocrine complications and treatment outcomes.
- Focus areas include insulin response in beta-thalassemia, screening programs, and the effects of multi-modal treatments on growth and development in sickle cell disease.
Key Insights:
- Investigates insulin response patterns during Oral Glucose Tolerance Test (OGTT) in young, transfused beta-thalassemia patients.
- Examines immigration and screening strategies for hemoglobinopathies across Italy, Spain, and Turkey.
- Analyzes the impact of blood transfusions, iron chelation, and hydroxyurea on puberty, growth, and spermatogenesis in sickle cell disease.
Outlook:
- This initiative aims to advance understanding and management of hemoglobinopathies.
- Future research will likely focus on optimizing treatment protocols and improving screening efficacy.
Abstract:
Starting from 2021, Acta Biomedica Parmensis will dedicate an annual update to the "Advances in Hemoglobinopathies". The section editor of this new editorial initiative is prof. Ashraf T Soliman, Pediatrician and Endocrinologist at Hamad Medical Center (HMC) of Doha. Prof Soliman is a pionier in the study of endocrine complications in hemoglobinopathies and effects of blood transfusions on spermatogenesis. He collaborates strictly with prof. Mohamed Yassin, Hematologist-Oncologist at MCH and the International Network of Clinicians for Endocrinopathies in Thalassemia and Adolescence Medicine (ICET-A). This issue of Acta Biomedica contains three articles on: The different patterns of insulin response during Oral Glucose Tolerance Test (OGTT) in transfused young patients with β- Thalassemia; Immigration and screening programs for hemoglobinopathies in Italy, Spain and Turkey and The effects of treatment with blood transfusion, iron chelation and hydroxyurea on puberty, growth and spermatogenesis in sickle cell disease,.
More Related Videos
11:59Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
Published on: September 6, 2017
05:23Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Related Concept Videos
Hemoglobin
When all four heme groups are bound to oxygen, the resulting molecule is called oxyhemoglobin. As a result, arterial blood...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
Disorders of Erythrocytes
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Gene Families
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Multiple Allele Traits