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Updated: Oct 21, 2025

High-throughput Screening for Protein-based Inheritance in S. cerevisiae
Published on: August 8, 2017
The dominant strain of SARS-CoV-2 is a mosaicism
Wei Wang1, Cheng-Peng Li1, Mei He1
1Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Science, Shandong Normal University, Jinan, Shandong 250014, China.
Abstract:
COVID-19 is seriously threatening human health all over the world. A comprehensive understanding of the genetic mechanisms driving the rapid evolution of its pathogen (SARS-CoV-2) is the key to controlling this pandemic. In this study, by comparing the entire genome sequences of SARS-CoV-2 isolates from Asia, Europe and America, and analyzing their phylogenetic histories, we found a lineage derived from a recombination event that likely occurred before March 2020. More importantly, the recombinant offspring has become the dominant strain responsible for more than one-third of the global cases in the pandemic. These results indicated that the recombination might have played a key role in the pandemic of the virus.
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