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Published on: June 17, 2025
Bronchial Anthracofibrosis and Tracheobronchomalacia
Mitra Samareh-Fekri1, Seyed Mehdi Hashemi Bajgani2, Ahmad Shafahi2
1Cardiovascular Research Center, Basic and Clinical Institute of Physiology, Kerman University of Medical Sciences, Kerman, Iran.
Tracheobronchomalacia (TBM) affects 9.38% of patients undergoing bronchoscopy. Age and anthracofibrosis are identified as key predictive factors for this respiratory condition.
Area of Science:
- Pulmonology
- Respiratory Medicine
- Medical Diagnostics
Background:
- Tracheobronchomalacia (TBM) involves softening of the trachea and bronchi, leading to respiratory issues.
- Limited data exists on TBM prevalence and associated risk factors.
- This study investigated TBM prevalence and predictive factors.
Purpose of the Study:
- To determine the prevalence of tracheobronchomalacia (TBM) in patients undergoing bronchoscopy.
- To identify demographic and clinical factors predictive of TBM.
- To explore the relationship between anthracofibrosis and TBM.
Main Methods:
- A cross-sectional study involving 1406 patients undergoing bronchoscopy.
- TBM defined by a ≥50% decrease in airway diameter during expiration.
- Patients were categorized into TBM cases and controls; data analyzed using logistic regression.
Main Results:
- The prevalence of TBM was 9.38% (132/1406); bronchomalacia was present in 16.66% of cases.
- Multivariable analysis identified older age (OR=1.02) and anthracofibrosis (OR=2.43) as significant predictors of TBM.
- A statistically significant association was found between age (P=0.03) and anthracofibrosis (P<0.0001) with TBM.
Conclusions:
- The study identified age and anthracofibrosis as significant predictive factors for TBM.
- Presence of anthracotic plaques may serve as a potential indicator for TBM.
- Findings contribute to understanding TBM epidemiology and risk stratification.
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