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Updated: Oct 21, 2025

Hydrophobic Salt-modified Nafion for Enzyme Immobilization and Stabilization
Published on: July 11, 2012
Biomimetic and biopolymer-based enzyme encapsulation
Friedrich Bialas1, Daniela Reichinger1, Christian F W Becker1
1Institute of Biological Chemistry, Faculty of Chemistry, University of Vienna, Austria.
Abstract:
Encapsulated enzymes are stable under various conditions and used in enzyme therapy, catalysis, and biosensors. The capsules are often inspired by structures from nature such as viral capsids, DNA motifs and diatom frustules. They are based on inorganic minerals as well as soft or polymeric materials, or even a combination of these. The choice of material influences the enzyme loading and response to heat, pH and presence of proteases. This review provides a comparison of enzyme encapsulation based on these different principles with a focus on materials inspired by nature.

