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Updated: Oct 21, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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A concise access to bridged [2,2,1] bicyclic lactones with a quaternary stereocenter via stereospecific

Shuailong Li1, Zhuangxing Li1, Mingzheng Li1

  • 1Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Engineering Research Center of Organosilicon Compounds & Materials, Ministry of Education, Sauvage Center for Molecular Sciences, Wuhan University, Wuhan, China.

Nature Communications
|September 7, 2021
PubMed

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