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Related Experiment Video

Updated: Oct 21, 2025

Non-Invasive Modulation and Robotic Mapping of Motor Cortex in the Developing Brain
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TMS Motor Mapping Methodology and Reliability: A Structured Review.

Rachel E Sondergaard1,2, Davide Martino1,2, Zelma H T Kiss1,2,3

  • 1Department of Clinical Neuroscience, University of Calgary, Calgary, AB, Canada.

Frontiers in Neuroscience
|September 7, 2021
PubMed
Summary
This summary is machine-generated.

This review synthesizes literature on transcranial magnetic stimulation (TMS) motor mapping parameters. It details how six key elements influence map outcomes, aiding study design and interpretation.

Keywords:
TMS methodologycentre of gravityhotspotmotor cortexmotor mappingmuscle mappingneuronavigationtranscranial magnetic stimulation

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Area of Science:

  • Neuroscience
  • Neurophysiology
  • Medical Imaging

Background:

  • Transcranial magnetic stimulation (TMS) is a non-invasive technique used to probe motor cortical representation.
  • Motor mapping via TMS is influenced by several controllable parameters, affecting map characteristics.

Purpose of the Study:

  • To review the literature on six key motor mapping parameters.
  • To discuss the influence of these parameters on outcome measures.
  • To explore factors affecting the selection of these parameters.

Main Methods:

  • A comprehensive literature review was conducted.
  • 132 out of 1,587 distinct records were analyzed in detail.
  • Information was synthesized to form the basis of the review.

Main Results:

  • Key motor mapping parameters and their impact on outcome measures are summarized.
  • Feasibility considerations for each parameter are reported.
  • Guidance is provided for designing and interpreting TMS mapping studies.

Conclusions:

  • Understanding motor mapping parameters is crucial for consistent and reliable TMS studies.
  • The selection of parameters significantly influences the resulting motor maps.
  • This review supports informed decision-making in TMS motor mapping research.