Related Experiment Video
Updated: Oct 21, 2025

08:05
Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice
Published on: June 29, 2022
3.0K
Atrial Fibrillation in Aging and Frail Mice: Modulation by Natriuretic Peptide Receptor C
Hailey J Jansen1, Motahareh Moghtadaei1, Sara A Rafferty2
1Department of Cardiac Sciences, Department of Physiology and Pharmacology, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada (H.J.J., M.M., R.A.R.).
Circulation. Arrhythmia and Electrophysiology
|September 7, 2021
Abstract:
[Figure: see text].
Related Concept Videos
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
581
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
581
Heart Failure II: Pathophysiology
106
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
106

