Related Experiment Video

Updated: Oct 21, 2025

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice
08:05

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice

Published on: June 29, 2022

3.0K

Atrial Fibrillation in Aging and Frail Mice: Modulation by Natriuretic Peptide Receptor C

Hailey J Jansen1, Motahareh Moghtadaei1, Sara A Rafferty2

  • 1Department of Cardiac Sciences, Department of Physiology and Pharmacology, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada (H.J.J., M.M., R.A.R.).

Circulation. Arrhythmia and Electrophysiology
|September 7, 2021
PubMed

Abstract:

[Figure: see text].

Keywords:
agingatrial fibrillationelectrophysiologyfibrosisfrailty

More Related Videos

Isolation of Atrial Myocytes from Adult Mice
08:34

Isolation of Atrial Myocytes from Adult Mice

Published on: July 25, 2019

10.8K
Programmed Electrical Stimulation in Mice
07:29

Programmed Electrical Stimulation in Mice

Published on: May 26, 2010

20.8K

Related Experiment Videos

Last Updated: Oct 21, 2025

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice
08:05

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice

Published on: June 29, 2022

3.0K
Isolation of Atrial Myocytes from Adult Mice
08:34

Isolation of Atrial Myocytes from Adult Mice

Published on: July 25, 2019

10.8K
Programmed Electrical Stimulation in Mice
07:29

Programmed Electrical Stimulation in Mice

Published on: May 26, 2010

20.8K

Related Concept Videos

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

581
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
581
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

106
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
106

Articles linked to this work by shared authors, journal, and citation graph.

Disturbed Repolarization-Relaxation Coupling During Acute Myocardial Ischemia Permits Systolic Mechano-Arrhythmogenesis.

Circulation research·2025

Lifelong longitudinal assessment of the contribution of multi-fractal fluctuations to heart rate and heart rate variability in aging mice: role of the sinoatrial node and autonomic nervous system.

GeroScience·2024

Natriuretic Peptide Receptor B Protects Against Atrial Fibrillation by Controlling Atrial cAMP Via Phosphodiesterase 2.

Circulation. Arrhythmia and electrophysiology·2023

PDE4D mediates impaired β-adrenergic receptor signalling in the sinoatrial node in mice with hypertensive heart disease.

Cardiovascular research·2023

Chronic testosterone deficiency increases late inward sodium current and promotes triggered activity in ventricular myocytes from aging male mice.

American journal of physiology. Heart and circulatory physiology·2023

Loss of Natriuretic Peptide Receptor C Enhances Sinoatrial Node Dysfunction in Aging and Frail Mice.

The journals of gerontology. Series A, Biological sciences and medical sciences·2021

Transmurality and Autonomic Effects of Pulsed Field Ablation on the Mitral Isthmus.

Circulation. Arrhythmia and electrophysiology·2026

Left Atrial Appendage Closure Versus Oral Anticoagulation in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Circulation. Arrhythmia and electrophysiology·2026

Pulsed Field Ablation Therapy Parameters: Enhancing Lesion Depth While Reducing Musculoskeletal Stimulation and Thermal Response in an Irrigated Tip Catheter: A Comprehensive Study Using In Silico, In Vitro, and In Vivo Models.

Circulation. Arrhythmia and electrophysiology·2026

Isochronal Versus Electrogram-Based Conduction Velocity Estimation to Predict Inducible Monomorphic Ventricular Tachycardia in Repaired Tetralogy of Fallot.

Circulation. Arrhythmia and electrophysiology·2026

Innervation of the Human Atrioventricular Node via the Inferior Pyramidal Space: Characterization Using Intersectional Strategies.

Circulation. Arrhythmia and electrophysiology·2026

Effect of Left Atrial Size and Volume Reduction on Pulmonary Vein Isolation Efficacy in Patients With Persistent and Longstanding Persistent Atrial Fibrillation: Subset Analysis From the aMAZE Trial.

Circulation. Arrhythmia and electrophysiology·2026

Berberine induces PD-L1 degradation via the autophagy-lysosome pathway through the PI3K-Akt pathway and enhances immunogenic cell death in triple-negative breast cancer.

Frontiers in immunology·2026

Cell cycle regulators contribute to extravillous trophoblast cell differentiation and function.

Human reproduction (Oxford, England)·2026

Mendelian randomization study of smoking exposure in relation to primary ovarian failure.

Medicine·2026

Analyzing structural and temporal dynamics of the Drosophila cancer studies: A bibliometric study from 1990 to 2024.

Medicine·2026

eIF4A1 enhances p70S6K mRNA translation and promotes nuclear β-catenin levels to augment stemness and metastasis in gastric cancer cells.

Biochemical pharmacology·2026

Fluoride induced chondrocyte extracellular matrix degradation by inhibition of glycolysis by the PHD2/HIF1α signaling pathway.

Environmental toxicology and pharmacology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us