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Updated: Oct 21, 2025

Preparation, Purification, and Use of Fatty Acid-containing Liposomes
Published on: February 9, 2018
Unprecedented formation of sterically stabilized phospholipid liposomes of cuboidal morphology
Pavel Bakardzhiev1, Aleksander Forys2, Barbara Trzebicka2
1Institute of Polymers, Bulgarian Academy of Sciences, Akad. G. Bonchev St., Bl. 103-A, 1113 Sofia, Bulgaria. rangelov@polymer.bas.bg.
Abstract:
Sterically stabilized phospholipid liposomes of unprecedented cuboid morphology are formed upon introduction in the bilayer membrane of original polymers, based on polyglycidol bearing a lipid-mimetic residue. Strong hydrogen bonding in the polyglycidol sublayers creates attractive forces, which, facilitated by fluidization of the membrane, bring about the flattening of the bilayers and the formation of cuboid vesicles.
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