Thinking Clearly About Biology and Childhood Adversity: Next Steps for Continued Progress

In a previous Perspectives article, we described conceptual problems that pose challenges for research on the effects of childhood adversity and offered promising directions for future research on this topic. In a commentary on that article, McLaughlin et al. disagree with some of these criticisms and defend the utility of their current approaches. Here, we briefly summarize where these perspectives overlap and diverge, using the exchange of views to highlight pressing gaps in knowledge that can be addressed through continued empirical research.