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Spousal similarities in cardiometabolic risk factors: A cross-sectional comparison between Dutch and Japanese data
Naoki Nakaya1, Tian Xie2, Bart Scheerder3
1Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan; Tohoku University Graduate School of Medicine, Sendai, Japan; Department of Health Science, Saitama Prefectural University, Japan.
Insights
Spouses share similar cardiometabolic risk factors, with Dutch couples showing stronger similarities in traits and lifestyle than Japanese couples. Age and cultural factors influence these spousal similarities in health.
Area of Science:
- Cardiology
- Epidemiology
- Human Genetics
Background:
- Limited research exists on spousal concordance of cardiometabolic risk factors across diverse populations.
- Understanding these similarities can offer insights into shared environmental and lifestyle influences on health.
Purpose of the Study:
- To quantify and compare spousal similarities in cardiometabolic risk factors and diseases.
- To investigate differences in spousal concordance between Dutch and Japanese populations.
Main Methods:
- Cross-sectional study of 28,265 Dutch and 5,391 Japanese spouse pairs.
- Analysis of cardiometabolic risk factors using correlation and logistic regression, adjusted for age.
- Comparison of spousal similarities across different risk factors and demographic groups.
Main Results:
- Significant spousal similarities were observed for all cardiometabolic risk factors and diseases in both cohorts.
- Strongest correlations were found in anthropometric traits, with Dutch pairs showing greater similarity than Japanese pairs.
- Spousal concordance varied by risk factor and age, with notable differences in hypertension and smoking between the Dutch and Japanese cohorts.
Conclusions:
- Spouses exhibit similarities in cardiometabolic risk factors in both Dutch and Japanese populations.
- Regional and cultural factors significantly influence the degree of spousal concordance in health behaviors and risk factors.
Background And Aims:
Few studies have examined and compared spousal concordance in different populations. This study aimed to quantify and compare spousal similarities in cardiometabolic risk factors and diseases between Dutch and Japanese populations.
Methods:
This cross-sectional study included 28,265 Dutch Lifelines Cohort Study spouse pairs (2006-2013) and 5,391 Japanese Tohoku Medical Megabank Organization (ToMMo) Cohort Study pairs (2013-2016). Spousal similarities in cardiometabolic risk factors were evaluated using Pearson's correlation or logistic regression analyses adjusted for spousal age.
Results:
The husbands' and wives' average ages in the Lifelines and ToMMo cohorts were 50.0 and 47.7 years and 63.2 and 60.4 years, respectively. Significant spousal similarities occurred with all cardiometabolic risk factors and diseases of interest in both cohorts. The age-adjusted correlation coefficients ranged from 0.032 to 0.263, with the strongest correlations observed in anthropometric traits. Spousal odds ratios [95% confidence interval] for the Lifelines vs. ToMMo cohort ranged from 1.45 (1.36-1.55) vs. 1.20 (1.05-1.38) for hypertension to 6.86 (6.30-7.48) vs. 4.60 (3.52-6.02) for current smoking. An increasing trend in spousal concordance with age was observed for sufficient physical activity in both cohorts. For current smoking, those aged 20-39 years showed the strongest concordance between pairs in both cohorts. The Dutch pairs showed stronger similarities in anthropometric traits and lifestyle habits (smoking and drinking) than their Japanese counterparts.
Conclusions:
Spouses showed similarities in several cardiometabolic risk factors among Dutch and Japanese populations, with regional and cultural influences on spousal similarities.
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