Spousal similarities in cardiometabolic risk factors: A cross-sectional comparison between Dutch and Japanese data

Naoki Nakaya1, Tian Xie2, Bart Scheerder3

  • 1Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan; Tohoku University Graduate School of Medicine, Sendai, Japan; Department of Health Science, Saitama Prefectural University, Japan.

Atherosclerosis
|September 7, 2021
PubMed

Insights

Spouses share similar cardiometabolic risk factors, with Dutch couples showing stronger similarities in traits and lifestyle than Japanese couples. Age and cultural factors influence these spousal similarities in health.

Area of Science:

  • Cardiology
  • Epidemiology
  • Human Genetics

Background:

  • Limited research exists on spousal concordance of cardiometabolic risk factors across diverse populations.
  • Understanding these similarities can offer insights into shared environmental and lifestyle influences on health.

Purpose of the Study:

  • To quantify and compare spousal similarities in cardiometabolic risk factors and diseases.
  • To investigate differences in spousal concordance between Dutch and Japanese populations.

Main Methods:

  • Cross-sectional study of 28,265 Dutch and 5,391 Japanese spouse pairs.
  • Analysis of cardiometabolic risk factors using correlation and logistic regression, adjusted for age.
  • Comparison of spousal similarities across different risk factors and demographic groups.

Main Results:

  • Significant spousal similarities were observed for all cardiometabolic risk factors and diseases in both cohorts.
  • Strongest correlations were found in anthropometric traits, with Dutch pairs showing greater similarity than Japanese pairs.
  • Spousal concordance varied by risk factor and age, with notable differences in hypertension and smoking between the Dutch and Japanese cohorts.

Conclusions:

  • Spouses exhibit similarities in cardiometabolic risk factors in both Dutch and Japanese populations.
  • Regional and cultural factors significantly influence the degree of spousal concordance in health behaviors and risk factors.
Abstract

Related Concept Videos

Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
828
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
267
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
437
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
513
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
553
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
14.7K