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Updated: Oct 21, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Fitting places in knowledge translation: Biomedical innovation in healthcare practice
1Faculty of Management, University of New Brunswick, 7 Macaulay Lane, 255 Singer Hall, Fredericton E3B 5A3, Canada.
Abstract:
The purpose of this study is to examine and further develop knowledge translation in the context of a biomedical device industry. Studies have yet to explain how science-based innovation is first reduced to practice in development of new biomedical technologies. To understand how this occurs, I investigated research and commercial product development in the powered prosthetic arm industry from 1945 to 2020. The findings demonstrate the foundational roles of basic knowledge translation in the production of new knowledge for the powered upper limb industry, and integrated knowledge translation in hospital and clinic-based development of powered hands. The focus on a biomedical engineering industry limits the generalizability of the findings. Future research directions include examination of other cases to identify practices in embedding research projects in locations-of-use as well as virtual fitting spaces.
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