Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Inhaled Medications

Inhaled Medications

Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...

COPD: Management Using Bronchodilators and Corticosteroids

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...

Chronic Obstructive Pulmonary Disease-V: Management

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment

Drugs Used in Lower Respiratory Disorders: Overview

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[COPD inhaled therapy narrative review].

Semergen·2024

Same author

[Foot color change after COVID19].

Semergen·2021

Same author

[Migraines, candidiasis and acne. One solution].

Semergen·2018

Same author

[COPD, what is the best treatment?]

Semergen·2018

Same author

[Pruritus and rivaroxaban].

Semergen·2018

Same author

[Hereditary leiomyomatosis and renal cell cancer].

Semergen·2016

Search research articles

Related Experiment Video

Updated: Oct 21, 2025

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

[COPD inhaled therapy narrative review].

A L Aguilar-Shea¹, C Gallardo-Mayo²

¹Medicina Familiar y Comunitaria, Centro de Salud Puerta de Madrid, Atención Primaria de Madrid, Madrid, España.

|September 8, 2021

Summary

This summary is machine-generated.

Long-acting bronchodilators are key for COPD management. Fixed long-acting muscarinic antagonist/long-acting beta-agonist inhalers offer superior symptom control compared to other combinations in COPD patients.

Keywords:

Chronic obstructive pulmonary disease Enfermedad pulmonar obstructiva crónica Exacerbación Exacerbation Inhaler therapy Terapia inhaladora

More Related Videos

Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals

Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals

Published on: March 30, 2017

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Related Experiment Videos

Last Updated: Oct 21, 2025

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals

Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals

Published on: March 30, 2017

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Area of Science:

Pulmonology
Pharmacology
Respiratory Medicine

Background:

Long-acting bronchodilators form the cornerstone of pharmacological treatment for Chronic Obstructive Pulmonary Disease (COPD).
Optimizing inhaled therapy is crucial for improving patient outcomes and disease control.

Purpose of the Study:

To compare the efficacy of different inhaled bronchodilator combinations for COPD management.
To identify inhaled therapies that provide superior symptom control in non-exacerbating COPD patients.

Main Methods:

A systematic literature search was conducted in Medline (PubMed) for comparative studies on inhaler therapy in COPD patients.
Analysis focused on studies comparing fixed combinations of long-acting beta-agonists/long-acting muscarinic antagonists (LABA/LAMA) versus long-acting beta-agonists/corticosteroids (LABA/ICS).
Further comparisons included individual long-acting muscarinic antagonists (LAMAs) versus long-acting beta-agonists (LABAs) and triple therapy regimens.

Main Results:

Fixed LABA/LAMA combinations demonstrated better disease control than LABA/ICS in non-exacerbating COPD patients.
Within LABA/ICS combinations, budesonide/formoterol showed superior control.
LAMAs alone showed comparable efficacy to LABAs, but offered better control when compared directly to LABAs.
Single-device triple therapy was superior to dual therapy and two-device triple therapy, with no significant differences among available single-device combinations.

Conclusions:

Fixed LABA/LAMA combinations represent a highly effective treatment strategy for enhancing COPD control.
Single-device triple therapy offers advantages over dual therapy and multi-device triple therapy for managing COPD.
Treatment decisions should consider the specific combination and delivery device for optimal patient outcomes.