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Prenatally diagnosed pseudoaneurysm of mitral-aortic intervalvular fibrous area

W J Hogan1, R Punn2, P Dean3

  • 1Department of Pediatrics, Division of Pediatric Cardiology, The University of California, San Francisco, CA, USA.

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
|September 8, 2021
PubMed

Insights

Congenital pseudoaneurysm of the mitral-aortic intervalvular fibrosa (MAIVF) is a rare condition. This study identifies 11 cases, highlighting its prenatal detection and varying clinical significance in fetuses.

Area of Science:

  • Cardiovascular Medicine
  • Fetal Cardiology
  • Congenital Heart Disease

Background:

  • The mitral-aortic intervalvular fibrosa (MAIVF) is a critical fibrous structure connecting the mitral and aortic valves.
  • Pseudoaneurysms of the MAIVF are uncommon, typically reported in adults post-cardiac events or in children after surgery/endocarditis.
  • Congenital MAIVF pseudoaneurysms are exceptionally rare, with limited published data.

Observation:

  • This study details five cases of congenital MAIVF pseudoaneurysm identified prenatally.
  • An additional six cases were diagnosed postnatally, expanding the known cohort.
  • The condition was observed to be either isolated or associated with complex congenital heart disease.

Findings:

  • Congenital pseudoaneurysm of the MAIVF can be detected during fetal development.
  • These findings represent a significant expansion of the literature on this rare cardiac anomaly.
  • The clinical significance of congenital MAIVF pseudoaneurysm varies widely among affected individuals.

Implications:

  • Prenatal identification of MAIVF pseudoaneurysm allows for early monitoring and management strategies.
  • Understanding the spectrum of this condition aids in diagnosing and managing fetuses and neonates.
  • This research underscores the importance of advanced fetal echocardiography in detecting rare cardiac malformations.
Keywords:
congenitalfetalmitral-aortic intervalvular fibrosaprenatalpseudoaneurysm

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