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Updated: Oct 21, 2025

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Tuberculosis with multiarticular involvement diagnosed by positive acid-fast staining in synovial fluid: An unusual
Diego Chemello1, Raissa Massaia Londero Chemello2, Giovana Thomasi Jahnke2
1Department of Clinical Medicine, Health Science Center; Postgraduate Program Gerontology, Universidade Federal de Santa Maria, Santa Maria, Brazil.
Abstract:
Osteoarticular tuberculosis (TB) is an uncommon form of extrapulmonary TB, comprising approximately 5% of all TB and 10%-15% of extrapulmonary TB cases. Multifocal skeletal TB is rare and accounts for 10% of all osteoarticular TB cases. Sometimes, the diagnosis is difficult. The potential delay in the clinical diagnosis may be critical for patients since it can cause the spread of the infection from the bone to the adjacent joints and surrounding tissues. We present a rare case of military TB with multiarticular involvement in a patient with chronic tophaceous gout. The initial diagnosis was confirmed throughout the positive analysis for Ziehl-Nielsen acid-fast staining in synovial fluid of two different joints, which is unusual. The patient was treated with antituberculosis drugs and presented good recovery signs.
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