Related Experiment Video
Updated: Oct 21, 2025

In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
Infection after the use of INFIX in Pelvic Ring Injuries
Rahul Vaidya1, Karun Amar1, Derrek Woodbury1
1Detroit Medical Center, 5th Floor Heart Hospital, 311 Mack Avenue, Detroit, Michigan 48201, USA.
Introduction:
The purpose of this study is to report on infection with anterior subcutaneous internal pelvic fixation (INFIX) for pelvic ring injuries and the outcomes of treatment.
Methods:
An IRB-approved retrospective study was performed using trauma databases of a level one and level two trauma center from 2012-2018. Infection after the INFIX procedure was diagnosed in 10 of 179 cases. Treatment included formal irrigation and debridement, removal of the hardware, and culture-specific antibiotics. Patients were followed for a minimum of 12 months. Recorded outcomes include X-rays, Majeed scores, and the presence of any loss of reduction using reduction parameters.
Results:
Time to detect the infection was 54.2 ± 24.3 days (range 24-90, median 56 days). Staphylococcus aureus was the most common bacteria isolated. The average follow-up was 830 ± 170 days (range 575-1088 days). All patients went on to the radiographic union. There were no recurrent infections or osteomyelitis at the latest follow-up. Patients maintained their reduction after INFIX removal (KI), and Majeed scores ranged from 72 to 96 (seven good, three excellent).
Discussion:
Infections after using the INFIX procedure were dealt with by irrigating and debriding the wounds, removing the INFIX with culture-specific antibiotics for 2-6 weeks. Implants were maintained for at least 25 days, and there was no loss of reduction. There were no long-term sequelae noted in this small series or the literature review included in this paper.
Related Concept Videos
Endocarditis IV: Nursing Management
Endocarditis I: Introduction
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
Urinary Tract Infection II: Pathophysiology
Urinary Tract Calculi VI: Surgical Management
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

