Association between Clinical Risk Score (Heart, Grace and TIMI) and Angiographic Complexity in Acute Coronary...

Area of Science:

• Cardiology
• Interventional Cardiology
• Clinical Risk Stratification

Background:

• Clinical scores (GRACE, TIMI, HEART) are validated for predicting adverse events in Non-ST ACS.
• Their ability to assess coronary artery disease complexity via angiography is less established.

Purpose of the Study:

• Evaluate correlation between clinical scores (TIMI, GRACE, HEART) and anatomical complexity (SYNTAX score).
• Assess non-ST ACS patients undergoing cinecoronariography.

Main Methods:

• Transversal cohort study of 138 Non-ST ACS patients (July 2018 - Feb 2019).
• Pearson's correlation and ROC curve analysis used to compare clinical scores with SYNTAX score.

Main Results:

• Positive correlation found between SYNTAX score and HEART (ρ=0.29) and GRACE (ρ=0.18) scores (p<0.01).
• TIMI score correlation with SYNTAX was not statistically significant (p=0.08).
• HEART score demonstrated highest AUC (0.81) for predicting SYNTAX ≥32.

Conclusions:

• Clinical scores show a modest positive association with SYNTAX score in Non-ST ACS.
• Combined use of HEART and GRACE scores provides good accuracy for detecting angiographic complexity.