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Antigenic properties of fresh and lyophylised human dura mater
M Occhiogrosso1, A De Tommasi, G Vailati
1Chair of Neurosurgery of the University, Bari, Italy.
Journal of Neurosurgical Sciences
|July 1, 1987
Abstract:
The action of human fresh and lyophylised human dura mater on rat, rabbit and human serum complement has been analyzed with the aim of confirming and comparing the species-specific antigenicity of both substances. The results demonstrate that both fresh and lyophylised human dura mater induce a complement consumption on rat and rabbit serum. The phenomenon is related to the species-specific antigenic activity of the tissue, and it is only partially decreased by the lyophylisation procedure. The residual antigenic activity, however, doesn't limit the use of this material as a graft for dural defects repairs in humans.