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Vitamin D prophylaxis in infancy.

Sophie Jullien1

  • 1Barcelona Institute for Global Health, University of Barcelona, Barcelona, Spain. sophjullien@gmail.com.

BMC Pediatrics
|September 9, 2021
PubMed
Summary
This summary is machine-generated.

A daily vitamin D (cholecalciferol) dose of 400 IU is effective for infant bone health and rickets prevention. Universal supplementation until 12 months is strongly recommended for all infants.

Keywords:
25-hydroxyvitamin DInfantsRicketsVitamin D supplementation

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Area of Science:

  • Pediatrics
  • Nutritional Science
  • Public Health

Background:

  • Vitamin D deficiency is a global concern in infants.
  • Rickets and infections are significant health issues in early childhood.
  • Evidence-based guidelines for infant vitamin D supplementation are crucial.

Purpose of the Study:

  • To review evidence on vitamin D supplementation effectiveness in infancy.
  • To determine optimal vitamin D dosage and supplementation duration.
  • To assess the impact on rickets and infection prevention.

Main Methods:

  • Comprehensive literature search up to July 2019.
  • Analysis of existing recommendations and supporting evidence.
  • Summarization of systematic review findings and evidence certainty.

Main Results:

  • 400 IU daily vitamin D effectively improves bone health and prevents rickets.
  • Supplementation is well-tolerated with no associated toxicity.
  • Universal supplementation from birth to 12 months is strongly recommended.

Conclusions:

  • Daily 400 IU vitamin D is essential for infant bone health.
  • Universal supplementation is recommended for the first year of life.
  • Targeted supplementation is advised for at-risk children over 12 months.