Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

5.1K
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
5.1K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.3K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Distinct Innate and Adaptive Immune Modules Differentially Associate with HIV Reservoir Size and Decay During Early Antiretroviral Therapy.

Cells·2026
Same author

All-two-dimensional, ion-gating synaptic transistors for high-temperature and ultralow-energy-consumption neuromorphic applications.

Science advances·2026
Same author

A preS2 aa1-26-specific humoural response marks functional cure in chronic HBV infection.

EBioMedicine·2026
Same author

Comparative Characterization of Lipid Composition and Minor Components in Coffee Oils from Arabica and Robusta Spent Coffee Grounds.

Foods (Basel, Switzerland)·2026
Same author

Body temperature drives azole tolerance in Candida albicans by hindering the autophagic degradation of Erg11.

Microbiological research·2026
Same author

Life and legacy in biophysics: 100th anniversary of Kechun Lin's birth.

Biophysical reviews·2026

Related Experiment Video

Updated: Oct 21, 2025

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model
07:50

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model

Published on: September 3, 2020

4.7K

Mesenchymal stem cell therapy for severe COVID-19.

Lei Shi1, Lifeng Wang1, Ruonan Xu1

  • 1Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, 100039, Beijing, China.

Signal Transduction and Targeted Therapy
|September 9, 2021
PubMed
Summary

Mesenchymal stem cell (MSC) therapy shows promise for treating severe COVID-19 by reducing lung damage and improving patient recovery. Clinical trials indicate MSCs offer safety and immune tolerance for coronavirus disease 2019 patients.

More Related Videos

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
04:09

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers

Published on: March 3, 2023

3.3K
Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
11:22

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

17.6K

Related Experiment Videos

Last Updated: Oct 21, 2025

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model
07:50

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model

Published on: September 3, 2020

4.7K
Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
04:09

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers

Published on: March 3, 2023

3.3K
Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
11:22

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

17.6K

Area of Science:

  • Immunology
  • Regenerative Medicine
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, presents a significant global health challenge with no specific treatments.
  • Severe COVID-19 can cause immune dysregulation and damage to both innate and adaptive immune responses, leading to lung injury.

Purpose of the Study:

  • To review the current progress of mesenchymal stem cell (MSC) therapy for COVID-19.
  • To highlight the therapeutic potential of MSCs in managing immune disorders and lung damage associated with SARS-CoV-2 infection.

Main Methods:

  • Summary of findings from clinical trials investigating MSC therapy in COVID-19 patients.
  • Review of the immunomodulatory and regenerative properties of MSCs relevant to COVID-19.

Main Results:

  • MSC treatment has demonstrated significant reduction in lung damage in COVID-19 patients.
  • MSC therapy has shown to improve patient recovery, exhibiting safety and good immune tolerance.

Conclusions:

  • Mesenchymal stem cells represent a viable therapeutic strategy for severe COVID-19.
  • Further research and clinical application of MSC therapy are warranted to address challenges in treating SARS-CoV-2-induced complications.