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Updated: Oct 21, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Factitiously Elevated Total Triiodothyronine in a Euthyroid Patient with Multiple Myeloma
Kaushik Mandal1, Damilola Ashorobi1, Alice Lee1
1Division of Endocrinology, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA.
Abstract:
Sporadic reports of factitious elevations of thyroid hormones related to laboratory interference from autoantibodies and multiple myeloma paraproteins have appeared in the literature. Such clinically confusing laboratory results can lead to erroneous diagnoses and inappropriate treatments. We report an additional case of a patient with multiple myeloma and an IgG paraproteinemia who had such a spurious elevation of total T3 complicating her levothyroxine management of hypothyroidism. In addition, we alert clinicians that differences in performance characteristics between various manufacturers' test platforms may also cause spurious reports.
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